Upstream Process Development & Manufacturing Associate

· San Diego, California
Employment Type Full-Time
Compensation DOE+Benefits+Options



Sorrento is a clinical stage, antibody-centric, biopharmaceutical company developing new therapies to turn malignant cancers into manageable and possibly curable diseases. Sorrento's multimodal multipronged approach to fighting cancer is made possible by its' extensive immuno-oncology platforms, including key assets such as fully human antibodies ("G-MAB™ library"), clinical stage immuno-cellular therapies ("CAR-T"), intracellular targeting antibodies ("iTAbs"), antibody-drug conjugates ("ADC"), and clinical stage oncolytic virus ("Sephrevir®").


We attract smart people who play well with others. We're small enough for your ideas to make a big impact, and large enough to offer you opportunities to grow professionally at any stage of your career.


If you’re a quick learner, enjoy working in the biotech industry, and share our mission of providing ground-breaking impact to medicine, each other, and our patients, Sorrento Therapeutics is the place for you!




Our Upstream Antibody Process Development & Manufacturing team is currently seeking an Upstream Associate who will be responsible for performing Upstream process development and manufacturing tasks including cell culture, cell banking, media preparation, benchtop bioreactor operation, and assistance in single use bioreactors operation for production of clinical and commercial products.




Job responsibilities will include but not be limited to:


  • Control and track raw material inventory
  • Maintain and clean cleanroom facility and equipment
  • Perform daily monitoring of equipment and assist Facilities and Engineering personnel as necessary on equipment maintenance and calibration
  • Prepare media and buffer solutions
  • Maintain cell culture flasks using good aseptic techniques
  • Record cell culture process development activities and results in appropriate notebooks and spreadsheets
  • Assist in the operation of Single-Use Bioreactors, including the Wave Cellbag bioreactors and HyPerforma 100L, 500L, and 2000L systems
  • Review and revise current Good Manufacturing Practice (cGMP), Batch Production Records, SOPs, protocols, and reports
  • Provide support to cross-functional teams to meet production or timeline demands
  • Demonstrate understanding in technical operations, safety, and cGMP
  • Ensure the completeness and accuracy of manufacturing documentation per approved procedures




  • Bachelor’s degree in a Life Sciences, Chemistry, or Chemical Engineering strongly preferred; cell culture experience is required
  • 1 to 3 years in a GMP environment with experience in GMP production including aseptic processing is a plus
  • Familiarity with cGMP, manufacturing, and data entry
  • Demonstrated ability to follow detailed directions in a manufacturing GMP environment
  • Must be familiar with Word and Excel




  • Support scientists who are on the leading edge of immunotherapies for the treatment of cancer. 
  • Earn a competitive salary that allows you to focus your attention on your passion.
  • A comprehensive benefits package including: medical, dental, vision, life and disability insurance, matching 401k, 10 paid holidays, and three-weeks’ PTO, plus stock options.


If this sounds like the right career to fit your interests, please apply. We’re looking forward to meeting you! 


Principals only. Recruiters, please don't contact this job poster. 

Sorrento Therapeutics, Inc. is an Equal Opportunity Employer

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  • Location
    San Diego, California
  • Employment Type
  • Compensation